Primate Gene Therapy

cynomolgus gene therapy

Diverse NHP species including Cynomolgus monkeys, Rhesus monkeys, African Green Monkeys, & Marmosets. Our Large colonies allow for rapid screening to obtain anti-AAV seronegative study candidates.

Large domestic breeding colonies allowing for NHP studies at any age range

Genetic, small molecule and protein-based biomarkers.

Monkey AAV Antibodies

Screening capability for array of anti-AAV antibodies and neutralizing antibodies serotypes including AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV7, AAV8, AAV9, AAVrh10, AAVhu68.

Barrier housing allowing for maintaining pre-screened AAV negative primates to support programs through completion with no study delays due to high seropositive rates or unexpected seroconversion.

Expert in multiple gene therapy delivery routes including:

Intrahepatic AAV Route - Primate

Intrahepatic

Intrathecal AAV Route - Primate

Intrathecal

Intraocular AAV Route - Primate

Intraocular

Intravenous AAV Route - Primate

Intravenous

Intratracheal AAV Route - Primate

Intratracheal

Intrahepatic AAV Route - Primate

Intrahepatic

Intrathecal AAV Route - Primate

Intrathecal

Intraocular AAV Route - Primate

Intraocular

Intravenous AAV Route - Primate

Intravenous

Intratracheal AAV Route - Primate

Intratracheal

Intramuscular AAV Route - Primate

Intramuscular

Intramuscular AAV Route - Primate

Intramuscular

Intranasal AAV Route - Primate

Intranasal

Intraperitoneal AAV Route - Primate

Intraperitoneal

Intracerebroventricular AAV Route - Primate

Intracerebroventricular

Intravitreal AAV Route - Primate

Intravitreal

Intranasal AAV Route - Primate

Intranasal

Intraperitoneal AAV Route - Primate

Intraperitoneal

Intracerebroventricular AAV Route - Primate

Intracerebroventricular

Intravitreal AAV Route - Primate

Intravitreal

cynomolgus gene therapy

Expert in repeated biopsies, surgical tissue excisions, and CSF sampling.

cynomolgus gene therapy

Partial or full sterile tissue collection with gene and protein expression quantification or samples shipped to sponsor.