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Naïve, protein-naïve and non-naïve study subjects.
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Pre-formulated liquid or solid dosage forms.
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Dose formulation for liquid forms with sample retention for analysis.
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Investigational and organ-specific toxicity evaluations (cardiac, hepatic, renal and respiratory)
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Full clinical chemistry, clinical pathology and clinical toxicology support.
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Neurotoxicity and immunotoxicity assessments
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Tissue-specific safety biomarker levels by biosampling, biopsy or microdialysis.
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Organ-specific or complete histology and pathology evaluation.