In Vitro Pharmacology and Toxicity
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Cytotoxicity on primary non-human primates cells (endothelial, epithelial, fibroblast, smooth muscle, hepatic, blood and bone marrow cells).
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Primate whole blood and PBMC cytokine release assay.
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Primate drug interaction CYP inhibition assays (liver microsomes and primary hepatocytes).
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Primate ABC drug transporter assays (primary and recombinant systems).