Core Laboratory Services
Full-Service Laboratory Support for Preclinical and IND-Enabling Studies
At Envol Biomedical, our Core Laboratory Services form the analytical backbone of every pharmacology, pharmacokinetics, and toxicology study we conduct. From bioanalytical chemistry to clinical pathology to advanced molecular assays, our lab team works in sync with our in vivo programs to deliver clean, accurate, and timely data—optimized for both scientific interpretation and regulatory submission.
Whether you’re running GLP-compliant studies or early discovery programs, Envol’s integrated lab infrastructure ensures fast, reliable results that move your program forward with clarity and confidence.
What We Offer
Our Core Laboratory Services are structured into three primary domains:
- Bioanalytical and Analytical Chemistry
We support method development and sample analysis for a wide range of compound types and study formats:
- Small molecules
- Biologics
- Oligonucleotides
- LNP-based formulations
Our services include:
- Formulation verification
- Dose confirmation
- Concentration analysis in various matrices
(Note: Mass spectrometry is not currently offered and is excluded by design to maintain focus on areas of expertise.)
- Clinical Pathology
Our clinical pathology lab supports full GLP-compliant evaluation of toxicology and pharmacology samples with rapid turnaround. Capabilities include:
- Hematology (CBC, differential)
- Clinical Chemistry (ALT, AST, BUN, creatinine, glucose, etc.)
- Urinalysis
- Coagulation Analysis
These services are tightly integrated into our study workflows to support both real-time monitoring and regulatory endpoints.
- Immunology and Molecular Assays
Our team specializes in ligand-binding assays and immunologic evaluations, including:
- Cytokine profiling using flow cytometry and multiplex platforms
- ELISA-based quantification
- Ligand-binding assays (LBA)
- Anti-drug antibody (ADA) testing
- PCR and ddPCR for gene expression, viral load, and biodistribution assessments
These assays are particularly valuable in support of biologics, gene therapy, and LNP-delivered modalities.
Flexible Support for Complex Study Types
Whether you’re conducting exploratory PK or a formal GLP toxicology study, our lab capabilities are tailored to meet evolving program needs. Our services are used to:
- Quantify drug exposure
- Track immune responses
- Identify toxicity markers
- Support regulatory safety data packages
We routinely customize lab panels and workflows based on study endpoints, regulatory requirements, and therapeutic modality.
Integration Across Capabilities
The Core Laboratory operates in direct coordination with:
- Pharmacokinetics (PK) – for quantitation and modeling
- Toxicology – for clinical pathology and biomarker endpoints
- Pharmacology – for readouts of drug response and efficacy
- Surgical Capabilities – for sample collection and post-operative monitoring
This integration accelerates timelines, reduces handoffs, and improves overall data quality.
Why Sponsors Trust Envol’s Lab Team
- In-house analytical and clinical support for all studies
- Customizable panels for toxicology, PK, and pharmacology
- Rapid turnaround for both GLP and non-GLP programs
- Seamless integration with Resero reporting and LIMS
- Experienced lab staff with a focus on preclinical timelines
Minimal but Strategic Pathology Inclusion
While histopathology and anatomic pathology services are outsourced, Envol:
- Provides in-study sample preparation
- Coordinates with external pathologists
- Integrates pathology results into final reports
This approach keeps timelines tight and workflows streamlined.
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Let’s create a custom lab solution that works with your study—not against your timeline.