August 29, 2025
At Envol Biomedical, innovation in musculoskeletal diagnostics and regenerative medicine is more than a goal—it’s a daily practice. At Envol Biomedical, precision and innovation define everything we do. It is with this in mind that we are proud to share highlights from a recently published study showcasing our expertise in synovial fluid aspiration and targeted intra-articular injections performed under fluoroscopic guidance. During this study, our team successfully performed synovial fluid aspiration and targeted joint injections in both the shoulder and knee—procedures guided with real-time fluoroscopy to ensure accurate intra-articular access. This achievement reflects not only our technical expertise but also our broader commitment to advancing musculoskeletal diagnostics and therapies.
Precision-Guided Joint Procedures
During this study, fluoroscopic imaging confirmed correct needle placement within the joint, providing unparalleled accuracy and reinforcing patient safety. These procedures allowed for both synovial fluid sampling and targeted injections—critical steps in both diagnostic evaluation and therapeutic intervention. This imaging validation not only ensured accurate sampling and delivery but also reinforced the safety and efficacy of the procedure.
Why Synovial Fluid Matters
Knee injections and synovial fluid aspiration have long been pillars of orthopedic and rheumatologic practice. They provide valuable insights into conditions such as:
- Inflammatory arthritis
- Crystal arthropathies (gout, pseudogout)
- Septic arthritis
- Mechanical effusions
These capabilities are vital for:
- Traditional diagnostics such as inflammatory arthritis, gout, pseudogout, and septic arthritis
- Evaluating mechanical effusions and guiding clinical decision-making
- Building a foundation for novel therapeutic strategies in regenerative medicine
But at Envol Biomedical, we don’t stop at traditional applications.
Beyond Conventional Care: Innovation in Joint Diagnostics
Envol’s expertise extends far beyond standard practice. Through advanced methods such as Lipid Mediator Profiling (LMP), our team is pioneering ways to evaluate bioactive molecules in synovial fluid—offering insights into inflammation, resolution pathways, and opportunities for truly personalized interventions.
We also integrate biologic therapies, including PRP, cellular products, and investigational agents aimed at cartilage preservation and regeneration. With molecular data from aspirated fluid, we can help guide therapeutic targeting—shaping the future of clinical trials and precision medicine in musculoskeletal care.
Driving the Next Generation of MSK Research
By combining advanced imaging, specialized procedures, and cutting-edge science, Envol Biomedical is setting a new standard for joint health research and care. Our role in this published study reflects our ongoing mission: to bring innovation, accuracy, and patient-centered focus to every project we undertake.
We invite you to explore the published study and see firsthand how Envol Biomedical is driving progress in musculoskeletal diagnostics and therapies.
Why This Matters: Beyond Conventional Diagnostics
At Envol Biomedical, joint aspirations are not just about ruling out disease—they’re an entry point into the next generation of personalized musculoskeletal care.
Our advanced approaches include:
- Lipid Mediator Profiling (LMP): Uncovering bioactive lipid mediators in synovial fluid to better understand inflammation and resolution pathways. This data can help guide tailored therapeutic decisions.
- Biologic Therapies: Delivering platelet-rich plasma (PRP), cellular therapies, or investigational biologics designed to preserve cartilage and promote regeneration.
- Therapeutic Targeting: Using molecular data from synovial samples to inform clinical trials and individualized treatment strategies.
Commitment to Innovation
The successful demonstration of these techniques highlights Envol Biomedical’s role at the forefront of orthopedic and musculoskeletal research. By integrating advanced imaging, precision procedures, and cutting-edge molecular analysis, our team continues to drive meaningful progress for patients and sponsors alike.